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Pathogenesis (HIV)

"Molecular Cloning and Analysis of Functional Genes From HIV-1 Sequence Subtypes A through G."

Published in Vaccine Weekly, March 25th, 1996

According to an abstract submitted by the authors to the 3rd Conference on Retroviruses and Opportunistic Infections, held January 28 - February 1, 1996, in Washington, DC, "We PCR amplified, cloned, and sequenced complete gp160 coding regions of 35 primary (PBMC-propagated) HIV-1 isolates collected at major epicenters of the current AIDS pandemic. Phylogenetic analyses of full-length env sequences indicated that the panel included members of all major sequence subtypes of HIV-1 group M (clades A-G) as well as an intersubtype recombinant (F/B) from an infected individual in Brazil. In addition, all subtype E and three subtype G viruses initially classified on the basis of partial...

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