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HBV Vaccines

HBV-Specific Immune Response Seen in Trial

Published in Vaccine Weekly, April 1st, 1996

Cytel Corporation, San Diego, California, announced that the therapeutic vaccine, Theradigm-HBV, in a Phase II trial safely stimulated a hepatitis B-specific immune response in chronically infected patients.

Hepatitis B (HBV), a disease prevalent in approximately 350 million people worldwide, causes two million deaths annually. The only approved treatment in the U.S. is alpha interferon, which cures only a small percentage of patients and is often accompanied by undesirable side effects. Poor tolerance due to side effects associated with alpha interferon is believed to derive from stimulation of a general immune response that is not disease-specific.

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