Published in Vaccine Weekly, July 22nd, 1996
Many cancers are nonimmunogenic. Research has shown that the addition of a costimulatory molecule to cancer cells by gene transfection can help stimulate host immunity against the newly transfected cell.
The immune stimulating success of B7-1 gene transfection into nonimmunogenic tumor cells in animal models has led researchers to attempt this approach as an immunotherapeutic in nonimmunogenic human cancers.
J.Y. Djeu and colleagues from the University of Southern Florida College of Medicine submitted the results of...
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