Malaria Vaccines
"Plasmodium falciparum Circumsporozoite Vaccine Immunogenicity and Efficacy Trial with Natural Challenge Quantitation in an Area of Endemic Human Malaria of Kenya."
Published in Vaccine Weekly, August 12th, 1996
According to the authors' abstract of an article published in Vaccine, "It has been hypothesized that antibody induced by Plasmodium falciparum circumsporozoite protein vaccine would be effective against endemic human malaria. In a malaria endemic region of Kenya, 76 volunteers, in 38 pairs sleeping adjacently, were immunized with subunit circumsporozoite protein Asn-Ala-Asn-Pro tetrapeptide repeat-pseudomonas toxin A, or hepatitis B vaccine. After quinine and doxcycycline, volunteers were followed for illness daily, parasitemia weekly, antibody, T-lymphocyte responses, and treated if indicated. Anopheles mosquitoes vesting in houses were collected and tested for P....
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Source: Vaccine Weekly (1996-08-12)
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