"Plasmodium falciparum Malaria: Some Epidemiological Implications of Parasite and Host Diversity."

According to the author's abstract of an article published in Annals of Tropical Medicine and Parasitology, "Observations are accumulating concerning: (1) the antigenic diversity of Plasmodium falciparum; (2) the diversity of the genetic immune-competence of human hosts; (3) the associations between these diversities and disease, protection and defined immune responses; and (4) the possible mechanisms of acquired protection at different steps of the host-parasite interaction. These observations have led to speculations concerning the distribution of disease, the acquisition of protection, and vaccination prospects. Speculations on the latter have varied from pessimism about the...

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