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HIV Vaccines

"Immunization with Recombinant p17/p24:Ty Virus-Like Particles in Human Immunodeficiency Virus-Infected Persons."

Published in Vaccine Weekly, November 11th, 1996

According to the authors' abstract of an article published in Journal of Infectious Diseases, "In studies of the natural history of human immunodeficiency virus type 1 (HIV-1) infection, it has been repeatedly shown that higher-titer antibody responses to the HIV gag p24 protein correlate with less rapid disease progression. In HIV-negative persons, immunization with HIV-1 p17/p24:Ty virus-like particles (p24-VLP) induced humoral and cellular immune responses to p24. This construct was therefore studied as a potential immunotherapeutic agent with the objective of augmenting the immune response to p24 in a double-blind placebo-controlled trial involving 74 p24 antibody-positive,...

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