"Epidemiology of Invasive Pneumococcal Disease in Southern California: Implications for the Design and Conduct of a Pneumococcal Conjugate Vaccine Efficacy Trial."

According to the authors' abstract of an article published in Journal of Infectious Diseases, "Population-based prospective surveillance of invasive pneumococcal disease was done in Southern California from 31 March 1992 to 1 April 1995; 814 cases were identified, for an incidence of 12.5/100,000 persons/year. The incidence among persons less than or equal to 2, less than or equal to 5, and greater than or equal to 65 years of age was 145, 72, and 32/100,000, respectively. More than 95% of cases included bacteremia; incidence of meningitis was 0.8/100,000. Among children less than or equal to 2 years of age, 79% of isolates were obtained in the outpatient setting, compared with 16% of...

Want to see the full article?

• Purchase this article for only $3.00