Vaccine Development
"Development of a Parainfluenza Virus Type 1, 2, 3 Subunit Vaccine."
Published in Vaccine Weekly, December 16th, 1996
According to an abstract submitted by the authors to the 15th Annual Meeting of the American Society for Virology, held July 13-17, 1996, in Ontario, Canada, "Parainfluenza (PIV) virus types 1, 2, 3 have been identified as major viral pathogens responsible for severe respiratory tract infections in infants and young children. Previous attempts to produce an efficacious PIV-1, 2, 3 vaccine have been unsuccessful. A trivalent PIV-1, 2, 3 subunit vaccine containing the major immunogenic proteins has been prepared. The hemagglutinin-neuraminidase (HN) and fusion (F) surface glycoproteins were purified from detergent-solubilized viral proteins by ion-exchange chromatography and adjuvanted...
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Source: Vaccine Weekly (1996-12-16)
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