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"Randomised Trial of the Effect of Co-Administration with Acellular Pertussis DTP Vaccine on Immunogenicity of Haemophilus influenzae Type b Conjugate Vaccine."

Published in Vaccine Weekly, February 3rd, 1997

According to the authors' abstract of an article published in Lancet, "Background: Inclusion of new vaccines in vaccination programmes for children would be easier if they could be combined with existing vaccines. Vaccines containing acellular pertussis in the diphtheria/tetanus/pertussis (DTP-a) combination are expected to replace the conventional whole-cell vaccines (DTP-w). We tested the immunogenicity and safety of a combination of DTP-a with the Haemophilus influenzae type b (Hib) conjugate of Hib capsular polysaccharide and tetanus toxoid (PRP-T), and inactivated poliovirus vaccine (IPV). Methods: 120 infants were enrolled and randomised to four groups to receive...

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