Published in Vaccine Weekly, February 10th, 1997
Researchers I.P.M. Keet of the University of Alabama, Birmingham, and colleagues compared the human leukocyte antigen (HLA) types of three cohorts of homosexual men (MACS, n=139; DCG, n=102; and Amsterdam, n=140) who have been enrolled in prospective studies since they first seroconverted to HIV.
"The allele/haplotype-TAP combinations found in our analysis to be consistently correlated with time to AIDS probably are true, or close surrogates of, genetic determinants of HIV-1 disease progression," Keet et al. wrote in their presentation abstract for the 4th Conference on...
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