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Conference Coverage (Retrovirus)

MAC Vaccine Enters Trials in HIV+ Adults, Children

Published in Vaccine Weekly, March 3rd, 1997

Early clinical trials of a vaccine to prevent Mycobacterium avium complex (MAC) infection are underway in children and adults.

The vaccine consists of inactivated M. vaccae administered in three intradermal inoculations at two-month intervals.

C.F. Von Reyn and B.J. March of Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, presented data from the studies at the Fourth Conference on Retroviruses and Opportunistic Infections, held January 22-26, 1997, in Washington, D.C.

In the pediatric trial, 35 children ages 1 to 8 years with HIV infection and CD4 counts of at least 300 cells/(mu)L were randomized to...

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