Lyme Disease
Crystal Structure of Major Lyme Disease Antigen Described
Published in Vaccine Weekly, May 5th, 1997
Now a big piece of the puzzle has been found, and it is likely to lead to improved vaccines.
Researchers at the Brookhaven National Laboratory and the State University of New York have solved the crystal structure of the outer surface protein A (OspA) of Borrelia burgdorferi, the spirochete that causes Lyme disease.
"OspA has a number of intriguing features," wrote Hong Li and colleagues. "We suggest that the protein has a conserved function, possibly acting as a receptor or signal transducer."
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Source: Vaccine Weekly (1997-05-05)
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