Published in Vaccine Weekly, June 9th, 1997
Lymph nodes (LN) draining from a progressively growing tumor contain specifically sensitized T lymphocytes. Harvesting these lymphocytes, and then activating and expanding them in vitro with anti-CD3 and IL-2 before injecting them into sublethally irradiated tumor-bearing mice yields an adoptive immunotherapeutic effect.
S. Saffold, representing colleagues from the Cleveland Clinic Foundation, Cleveland, Ohio, presented research at the American Association for Cancer Research...
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