"Reactivity and Fine Specificity of Clonal and Oligoclonal T Cells Isolated from Melanoma Patients Vaccinated with gp100 Antigenic Peptides."

According to an abstract submitted by the authors to the 88th Annual Meeting of the American Association for Cancer Research, held April 12-16, 1997, in San Diego, California, "Recent identification and cloning of genes encoding tumor associated antigens (TM) expressed by human melanoma has led to the design and testing of a new immunologic treatment strategies for patients with metastatic melanoma. These strategies include immunizing patients with recombinant viruses encoding TM, immunizing patients with antigenic peptides derived from TM, and adoptive transfer of autologous PBL expanded in vitro with antigenic peptides derived from TAA. Substituting M for T at the position 2 anchor of...

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