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HAV Vaccines

"Safety and Immunogenicity of Inactivated Hepatitis A Vaccine in Patients with Chronic Liver Disease."

Published in Vaccine Weekly, July 28th, 1997

According to the authors' abstract of an article published in Journal of Medical Virology, "The safety and immunogenicity of inactivated hepatitis A vaccine was evaluated in patients with chronic liver disease. Sixty hepatitis A virus antibody (anti-HAV) seronegative patients with chronic liver disease (56 chronic hepatitis B and four chronic hepatitis C) and from 17 to 47 years of age received a dose of 1440 ELISA units of the inactivated hepatitis A vaccine at month 0, and a booster at month 6. Anti-HAV seroconversion (greater than or equal to 33 mlU/mL) was 57.6% (34/59) on day 15, and reached 93.2% (55/59) 1 month after primary vaccination. At month 6, the seropositivity of anti-HAV...

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