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Malaria Vaccines

Military Tests Gene-Based Vaccine at Fort Detrick

Published in Vaccine Weekly, July 28th, 1997

A company sponsoring the first human trials of a malaria vaccine made from the DNA of the parasite that causes the disease said the test holds promise for safer vaccines to protect against a wider variety of diseases.

The trial involving 20 volunteers at the Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, is conducted by Lt. Cmdr. Thong Le, Naval Medical Research Institute, Rockville, Maryland. The study is sponsored by Vical Inc., San Diego, California.

Unlike conventional vaccines made from killed or weakened organisms, genetic vaccines use just a snippet of the organism's genetic material. The DNA,...

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