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Poliovirus

"Rare Adverse Events Associated with Oral Poliovirus Vaccine in Brazil."

Published in Vaccine Weekly, August 11th, 1997

According to the author's abstract of an article published in Brazilian Journal of Medical and Biological Research, "Oral poliovirus vaccine (OPV) developed by A. Sabin has been effectively used to control poliomyelitis in Brazil, and the last case with the isolation of a wild poliovirus strain occurred in March 1989. Although the vaccine controlled the circulation of wild strains and poliomyelitis cases associated with these strains were not detected during the last eight years, rare cases classified as vaccine-associated paralytic poliomyelitis (VAPP) have been detected. Molecular characterization studies of poliovirus strains isolated from VAPP cases and from healthy contacts have...

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