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Cancer Vaccines

Immune Response Produced in Multiple Myeloma Patients

Published in Vaccine Weekly, August 11th, 1997

An idiotypic cancer vaccine produced a tumor-specific immune response in four of five multiple myeloma patients treated in a Phase I clinical trial.

The vaccine was developed by Genzyme Transgenics Corp., Framingham, Massachusetts. The clinical trial was conducted by researchers at the U.S. National Cancer Institute (NCI) and University of Arkansas for Medical Sciences (UAMS).

The tumor-specific response experienced by patients in the trial indicates the vaccine's potential ability to reduce or eliminate residual cancer in patients who have not responded to other therapies. Based on these preliminary results, the company will accelerate vaccine...

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