Published in Vaccine Weekly, December 8th, 1997
As one of the aims of anti-cancer vaccines is to treat established tumors, it is anticipated that several immunizations may be required. Research has shown, however, that strong host immune responses against viral proteins can inhibit the repetitive use of one vector medium.
Kari R. Irvine and colleagues from the National Cancer Institute and the National Institutes of Health, Maryland, suggested that the use of different vehicles for primary vaccination delivery and boosting...
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