AIDS Vaccines

Experimental Trial Combines DNA Vaccine With Triple-Drug Therapy To Stop HIV

Published in Vaccine Weekly, February 9th, 1998

Researchers at the University of Pennsylvania Medical Center are combining a proven anti-retroviral drug therapy with an experimental DNA vaccine in an effort to eradicate HIV in infected patients.

The drug regimen, in which three different agents that block HIV replication are given concurrently, has been shown to lower levels of the virus in many patients to levels undetectable by all but the most sensitive assays. Immune system function often is restored in individuals receiving this therapy, returning them to health. They cannot be considered cured, however, because the virus lingers quiescently in certain subpopulations of T cells.

The...

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Source: Vaccine Weekly (1998-02-09)

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