Mucosal Immunization
"Application of Liposomes for Development of Oral Vaccines: Study of in vitro Stability of Liposomes and Antibody Response to Antigen Associated with Liposomes after Oral Immunization."
Published in Vaccine Weekly, March 2nd, 1998
According to the authors' abstract of an article published in Journal of Veterinary Medical Science, "In order to evaluate the usefulness of liposomes as oral vaccines, the stability of liposomes and serum IgA antibody response to antigen associated with liposomes after oral administration were examined. Liposomes composed of dipalmitoylphosphatidylcholine (DPPC), dipalmitoylphosphatidylserine (DPPS), and cholesterol (Chol) (1:1:2, molar ratio), distearoylphosphatidylcholine (DSPC) and Chol (7:2, molar ratio), and DSPC, DPPS, and Chol (7:3:2 or 1:1:2, molar ratio) were stable in acidic solution (pH 2.0), bile, and pancreatin solution, whereas liposomes composed of DPPC and Chol (7:2,...
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Source: Vaccine Weekly (1998-03-02)
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