Cholera Vaccines

Vaccine in A French-Fry? Researcher Thinks So

Published in Vaccine Weekly, March 16th, 1998

U.S. researchers said they had genetically engineered potatoes to carry a vaccine against cholera, creating the possibility people could be inoculated by eating french fries.

"We anticipate that this system will be very useful in economically developing areas where cholera is endemic and where (other) vaccines don't work very well," said William Langridge, Loma Linda University in California, who led the study.

Langridge and colleagues genetically engineered potatoes to produce non-toxic cholera toxin B (CTB), a protein that sparks an immune response in mice and humans. The resulting potatoes are transgenic - containing both potato and foreign...

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Source: Vaccine Weekly (1998-03-16)

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