"Antibodies and Antibody-Secreting Cells in the Female Genital Tract After Vaginal or Intranasal Immunization with Cholera Toxin B Subunit or Conjugates."

According to the authors' abstract of an article published in Infection and Immunity, "We studied the antibody response including antibody-secreting cells (ASC) in the female genital tract of mice after mucosal immunizations with the recombinant B subunit of cholera toxin (rCTB) perorally, intraperitoneally, vaginally, and intranasally (i.n.). The strongest genital antibody responses as measured with a novel perfusion extraction method were induced after vaginal and i.n. immunizations, and these routes also gave rise to specific immunoglobulin A (IgA) and IgG ASC in the genital mucosa. Specific ASC in the iliac lymph nodes, which drain the female genital tract, were seen only after...

Want to see the full article?

• Purchase this article for only $3.00