"Enhanced and Prolonged Humoral and Cell Mediated Responses to Synthetic Malarial Peptide Microencapsulated in Biodegradable Microspheres."

According to an abstract submitted by the author to the conference New Trends in Vaccine R & D: Adjuvants, Delivery Systems, and Antigen Formulations, held February 26-28, 1998, in Cedex, France, "Biodegradable poly(lactide) and poly(lactide-co-glycolide) microspheres (PLA-MS; PLGA-MS) have been shown to be capable of eliciting strong and long-lasting antibody and T cell proliferative responses to encapsulated protein and peptide antigens. However, skill relatively little is known about the relevance of microsphere changes on the quality of the immune responses and, in particular, on the potential of MS to elicit cytotoxic T cell (CTL) response. Here, two peptides were used: (i) a...

Want to see the full article?

• Purchase this article for only $3.00