Published in Vaccine Weekly, May 11th, 1998
Vancomycin is the last line of defense against organisms that have acquired resistance to antimicrobial drugs. Species of Enterococcus faecalis - which occur among the normal intestinal flora of humans - are a major cause of urinary tract infections, wound infections, intra-abdominal abscesses, endocarditis, bacteremia, and many hospital-acquired infections including bacterial sepsis of newborns. An increasing number of these infections are caused by enterococci that have developed resistance to vancomycin.
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