DNA Vaccines
"Plasmid DNA: A New Era in Vaccinology."
Published in Vaccine Weekly, June 8th, 1998
According to the author's abstract of an article published in Biochemical Pharmacology, "DNA vaccination is a novel approach for inducing an immune response. Purified plasmid DNA containing an antigen's coding sequences and the necessary regulatory elements to express them is introduced into the tissue via intramuscular injection or particle bombardment. Once the DNA reaches the tissue, the antigen is expressed in enough quantity to induce a potent and specific immune response and to confer protection against further infections. The effectiveness of DNA vaccines against viruses, parasites, and cancer cells has been demonstrated in numerous animal models. This new approach comes as an...
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Source: Vaccine Weekly (1998-06-08)
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