Cancer Vaccines

Vaccine Kills Spreading Cancer in Animal Model

Published in Vaccine Weekly, June 22nd, 1998

Johns Hopkins University scientists have developed a vaccine that, in mice, can alert the immune system to the presence of stray cancer cells and significantly reduce their blood-borne spread.

"Metastatic cancer, or cancer that is spreading from its site of origin, is among the toughest stages of cancer to treat," said Hongxiu Ji, MD, postdoctoral fellow at Hopkins in Baltimore, Maryland. "Our findings suggest cancer vaccines could be an important tool for preventing and treating the spread of cancers."

Giving the vaccine prior to a tail vein injection of cancer cells prevented development of metastatic lung tumors in eight of 10 mice, while all...

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Source: Vaccine Weekly (1998-06-22)

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