Virology

First Detailed, 3-D Image of Surface Protein of AIDS Virus Derived

Published in Vaccine Weekly, June 29th, 1998

Researchers at Dana-Farber Cancer Institute and Columbia University, for the first time, have obtained a detailed, three-dimensional picture of the lock-and-key mechanism by which HIV-1 latches onto blood cells - a milestone in the effort to develop AIDS vaccines that are effective against many strains of the virus.

In four studies published in the June 18, 1998, issue of Nature and the June 19, 1998, issue of Science, researchers led by Joseph Sodroski, MD, of Dana-Farber in Boston, Massachusetts, and Wayne Hendrickson, PhD, of Columbia and the Howard Hughes Medical Institute in New York, reported that they have determined the precise structure of a protein on the...

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Source: Vaccine Weekly (1998-06-29)

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