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Vaccine Development (DiavaX)

Scientists Discover Action Mechanism of Diabetes Vaccine

Published in Vaccine Weekly, June 29th, 1998

Anergen, Inc., Redwood City, California, announced in a recent study that its functional genomics vaccine stimulates antibodies that target the interaction of autoreactive white blood cells in autoimmunity and protects diabetes-prone non-obese diabetic (NOD) mice from the onset and progression of diabetes.

The data was presented at the Annual Meeting of the American Diabetes Association (ADA) in Chicago, Illinois. Anergen anticipates that Phase I clinical (safety) trials of the compound, DiavaX, will be initiated within a year.

In the study, Anergen scientists treated NOD mice before development of diabetes symptoms (5 weeks) or after the onset of...

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