Vaccine Development

Reengineered Poliovirus an Effective Vector for in Murine Study

Published in Vaccine Weekly, September 7th, 1998

Researchers led by scientists at University of California at San Francisco say they have made a significant breakthrough in their attempt to re-engineer the poliovirus so that it could some day be used as a transporting mechanism for inducing immunity against disease pathogens in humans.

The finding, reported in a recent issue of Proceedings of the National Academy of Science, could ultimately have implications for developing re-engineered poliovirus vaccines for HIV, hepatitis B, other viral diseases and cancer, said the senior author of the study, Raul Andino, PhD, an assistant professor of microbiology at UCSF.

Recombinant viruses, engineered with...

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Source: Vaccine Weekly (1998-09-07)

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