Conference Coverage (12th World AIDS)

Vaccination With HIV DNA Induces Anti-HIV Chemokines

Published in Vaccine Weekly, September 7th, 1998

Animals vaccinated with a candidate AIDS vaccine have increased levels of anti-HIV chemokines.

In HIV infected chimpanzees, vaccination-induced increases in the chemokines correlated with decreased viral load and induction of other anti-HIV immune responses.

"DNA vaccines for HIV-1 may be an important tool to modulate in vivo levels of beta chemokines," suggested David Weiner of the University of Pennsylvania and colleagues. "The role of such modulation should be examined with regard to vaccine and immune therapy production."

Weiner et al. announced their findings in a poster presentation to the 12th World AIDS Conference, held...

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Source: Vaccine Weekly (1998-09-07)

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