Published in Vaccine Weekly, September 7th, 1998
Researchers found that prior vaccination with bacillus Calmette-Guerin boosted cellular immune response to purified protein derivative and heat shock protein 70 in mycobacteria-challenged guinea pigs, but the T cell response to heat shock protein 65 was not boosted.
"We believe that these data are inconsistent with a protective role for the heat shock protein (hsp) 65 in this model," R.A. Bartow and D.N. McMurray of the Texas A&M University Health Science Center wrote ("Cellular and Humoral Immune Responses to Mycobacterial Stress Proteins in Experimental...
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