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HBV Vaccines

"Efficacy of Hepatitis B Vaccines With and Without preS2-Region Product in Sumo Wrestlers in Japan."

Published in Vaccine Weekly, September 21st, 1998

According to the authors' abstract of an article published in Hepatology Research, "One hundred and twenty Sumo wrestlers in Japan received 20 (mu)g of a hepatitis B vaccine containing 20% (w/w) preS2-region product, while the other 181 received 10 (mu)g of the vaccine without preS2-region product, four times during 20 months. They were followed for antibody to hepatitis B surface antigen (anti-HBs) by passive hemagglutination up to 32 months after the first vaccination. The seroconversion to anti-HBs occurred more frequently in the wrestlers receiving preS2-plus vaccine than in those receiving preS2-minus vaccine at the end of observation (87% vs. 66%, P<0.001). Among the...

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