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Pneumonia

HIV-1 Infected Ugandans Respond Poorly to Pneumonia Vaccine

Published in Vaccine Weekly, November 2nd, 1998

HIV-1 infected adults in Uganda are susceptible to streptococcal pneumonia, but respond poorly to the vaccine.

N. French and colleagues at the University of Minnesota assessed the feasibility of establishing a pneumococcal vaccine trial among HIV-1-infected adults in a community clinic in Entebbe, Uganda, and to characterize their responses to 23-valent pneumococcal polysaccharide vaccine ("Pneumococcal Vaccination in HIV-1-Infected Adults in Uganda: Humoral Response and Two Vaccine Failures," AIDS, September 10, 1998;12(13):1683-1689).

An open-label pilot trial was used to evaluate recruitment and compliance of HIV-1-infected adults to vaccination...

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