Vaccine Development

Aged Mice Successfully Immunized with Myogenic DNA Vaccine

Published in Vaccine Weekly, November 9th, 1998

Pharmadigm Inc., Salt Lake City, Utah, presented data at IBC's 4th Annual Conference on Genetic Vaccines about its attempts to immunologically protect aged mice against a lethal virus challenge through DNA vaccination.

The DNA vaccine in this study incorporated Pharmadigm's proprietary myogenic gene-transfer vector.

Virologist John Gebhard, Pharmadigm Inc., reported on "DNA Vaccination and Immunological Protection of Aged Mice." In the experiment he described, the model assessed protection from genital herpes after infection with herpes simplex virus type 2 (HSV-2). The protective antigen encoded in the myogenic DNA vaccine is gD2, an important...

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Source: Vaccine Weekly (1998-11-09)

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