AIDS Vaccines

Chimp Protected Against HIV Typical of Clinical Strains

Published in Vaccine Weekly, November 30th, 1998

For the first time an HIV vaccine has protected a chimpanzee against infection with a viral strain similar to those circulating in humans.

The results are immensely encouraging for researchers pursuing AIDS vaccine strategies not based on a live, attenuated virus. Instead, the approach uses a live adenovirus (Ad-HIV) to deliver HIV antigens for priming and an HIV subunit vaccine for boosting.

Many HIV vaccine strategies are capable of protecting against challenge with the same HIV or SIV strain as those used in the vaccine preparations. A number of vaccine candidates have protected against heterologous challenge. But the current study is the first...

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Source: Vaccine Weekly (1998-11-30)

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