Published in Vaccine Weekly, December 21st, 1998
The answer isn't Methuselah-aged lymphocytes: these key immune cells turn over many times in a person's lifetime. Two modern theories compete. One is that persistent antigen (or re-exposure to a pathogen) must constantly provide restimulation to the immune system. The second admits that such restimulation can lead to very long-lasting memory, but suggests that it is not necessary for memory to last.
Now a mathematical...
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