Immunology

Species Variability in Adjuvant Response

Published in Vaccine Weekly, December 21st, 1998

Vaccine adjuvants use different immune pathways to immune responses, study findings suggest.

Vaccine adjuvants exert critical and unique influences on the quality of immune responses induced during active immunizations, noted George S.N. Hui and Caryn N. Hashimoto, University of Hawaii ("Pathways for Potentiation of Immunogenicity during Adjuvant-Assisted Immunizations with Plasmodium falciparum Major Merozoite Surface Protein 1," Infection and Immunity, November 1998;66:5329-5336).

Hui and Hashimoto studied the mechanisms of action of immunological adjuvants in terms of their requirements for cytokine-mediated pathways for adjuvanticity. ...

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Source: Vaccine Weekly (1998-12-21)

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