Conference Coverage (Retrovirus)

Antibody-Inducing Vaccine Could Prevent AIDS

Published in Vaccine Weekly, February 15th, 1999

Maybe antibodies can do the trick after all.

The most difficult problem facing AIDS vaccine researchers is that they don't know what protective immunity to HIV looks like. Studies of highly exposed, uninfected individuals and of people who remain healthy despite long-standing HIV infection indicate that cell-mediated - and not antibody-mediated- immune responses are desirable.

Now a monkey study shows that antibodies can indeed protect against HIV infection and disease.

"An HIV vaccine that induces neutralizing antibodies should have a protective effect against HIV infection and disease," said Walter Reed Army Institute...

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Source: Vaccine Weekly (1999-02-15)

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