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Human Papillomavirus

"Histologic and Immunologic Associations of an HPV16 Variant in LoSIL Smears."

Published in Vaccine Weekly, March 1st, 1999

According to the authors' abstract of an article published in Gynecologic Oncology, "Background : Human papillomavirus type 16 variants have been described and may have different biologic activities. This has implications for the design of HPV vaccines. Objectives: The aim of this study was to see if the HPV16 variant E-C 131 can be detected in women with preinvasive disease and to consider the histological and immunological implications of such infection. Design: A prospective observational cross-sectional study on a cohort of women with minor cervical cytological abnormalities was performed. Methods: Samples were tested for HPV DNA by polymerase...

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