"Tentative Vaccination of Mice with a Poliovirus cDNA Carrying Tumor Rejection Antigens from the Murine P815 Mastocytoma."

According to an abstract submitted by the authors to the Ninth International Congress on Anti-Cancer Treatment, held February 2-5, 1999, in Paris, France, "A nonapeptide encoded by the P1 gene of the murine mastocytorna cell line P815 carries tumor rejection antigens and in particular two epitopes, which are recognized by specific cytotoxic T lymphocyte (CTL) clones in the context of the major histocompatibility class I molecule L^d (Lethe and coll., Eur. J. Immunol., 1992, 22, 2283). It has been demonstrated that the poliovirus (PV) can be used as a vector for inducing a specific CTL response and protective immunity against a murine malignant melanoma (Mandl and coll., PNAS,...

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