Published in Vaccine Weekly, April 12th, 1999
The second most common cause of croup, bronchiolitis, and pneumonia in infants, after respiratory syncytial virus (RSV), is parainfluenza virus type 3 (PIV3). David Greenberg, MD, Children's Hospital of Pittsburgh, Pennsylvania, reported on a clinical study of bovine PIV3 vaccine that is administered by intranasal spray.
In the study, 192 infants were randomized to receive the intranasal vaccine or placebo at ages two, four, six, and 12-15 months. Other regularly scheduled childhood immunizations, such as the diptheria-tetanus-pertussis vaccine, were...
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