Vaccine Development

Successful DNA Immunization Against M. avium Reported

Published in Vaccine Weekly, August 9th, 1999

The first successful DNA vaccination against Mycobacterium avium has been reported by researchers in North Carolina.

Mycobacterium avium causes disseminated disease in humans with AIDS, paratuberculosis in ruminants, lymphadenopathy in swine, and tuberculosis in birds.

In this study, M. Velaz-Faircloth and colleagues from Durham, North Carolina's Veterans Affairs Medical Center constructed DNA vaccines expressing mycobacterial antigens as fusion proteins with enhanced green fluorescent protein (EGFP) ("Protection Against Mycobacterium avium by DNA Vaccines Expressing Mycobacterial Antigens as Fusion Proteins with Green...

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Source: Vaccine Weekly (1999-08-09)

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