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Drug Abuse

Progress Reported Toward Vaccine To Fight Cocaine Addiction

Published in Vaccine Weekly, August 30th, 1999

A potential vaccine against the addictive effects of cocaine was described at the National Meeting of the American Chemical Society, held in New Orleans, Louisiana, during August 1999.

Kim D. Janda, PhD, The Scripps Research Institute, La Jolla, California, said he has induced the immune system to create specific antibodies that attack the cocaine molecule and keep it from reaching its target - the central nervous system.

Cocaine does not produce antibodies because its molecule is too small to be recognized by the immune system. Janda said he has overcome this obstacle by attaching a cocaine derivative to a larger protein - an effect he calls...

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