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Conference Coverage (IHV)

HIV Fusion Dissected

Published in Vaccine Weekly, September 20th, 1999

HIV dances a deadly two-step as it locks onto its cellular partner.

A new tool developed by Edward A. Berger and colleagues at the U.S. National Institute of Allergy and Infectious Diseases shows that HIV must follow a carefully ordered sequence of events to infect a cell.

"The elucidation of the molecular interactions at the cell surface associated with HIV entry has led to new concepts for therapy and prevention of HIV infection," Berger said in a presentation to the 1999 Meeting of the Institute of Human Virology, held August 28-September 2 in Baltimore, Maryland, USA.

Berger and co-workers created a quantitative cell-to-cell...

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