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Candidiasis Vaccines

"Strain-Dependent Migration of Lymphocytes to the Vaginal Mucosa after Peripheral Immunization."

Published in Vaccine Weekly, October 25th, 1999

According to the authors' abstract of an article published in Immunogenetics, "We have previously demonstrated a genetic predisposition among mice regarding their ability to be protected against vaginal candidiasis after peripheral immunization. Both BALB/c and (BALB/cxC57BL/6) Fl mice are protected against vaginal candidiasis after subcutaneous immunization with Candida albicans extract and C57BL/6 mice are not protected by this immunization. In the present study, the ability of FI-derived immune cells to transfer protection to naive parental strains was observed in BALB/c recipient mice, but not apparent in B6 recipient mice. This result is highly suggestive that the...

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