Vector Development
Liver Still Elusive Holy Grail of Gene Therapy
Published in Vaccine Weekly, October 25th, 1999
A major recent advance comes from a German research group that finally has figured out a way to use liver-infecting viruses (hepadnaviruses such as hepatitis B virus) as a vector. But serious practical obstacles remain, warns Don Ganem of the Howard Hughes Medical Institute.
"We are therefore, still a long way from the routine use of hepadnaviruses in gene therapy," Ganem wrote in a commentary article that appeared in the Proceedings of the National Academy of Sciences ("An Advance in Liver-Specific Gene Delivery," PNAS,...
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Source: Vaccine Weekly (1999-10-25)
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