Malaria Vaccine

DNA Immunization Helps Malaria Vaccine Development

Published in Vaccine Weekly, November 1st, 1999

DNA-coated gold particles injected by a gene gun could be one component of an effective malaria vaccine strategy, say researchers from Dartmouth University, the University of Massachusetts Medical Center, and Osaka University.

In their study, A.A. Belperron and colleagues compared the ability of two vaccines, both made of DNA that codes for a protein (known as SERA) that appears on the surface of the malaria parasite during several stages in its life cycle, to elicit an immune response against the parasite in mice. The first vaccine consisted simply of DNA suspended in a saline solution that was injected into the leg while the second used a device called a gene gun to...

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Source: Vaccine Weekly (1999-11-01)

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