Published in Vaccine Weekly, November 1st, 1999
Janet E. McElhaney of Eastern Virginia Medical School, Norfolk, Virginia, and colleagues measured granzyme B responses to influenza vaccination in 100 frail, elderly patients. Granzyme B is the key enzyme involved in CTL-mediated cell killing, a major antiviral immune response.
"Granzyme B may be a cellular marker of vaccine efficacy in...
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