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Patent Issued Covering Treatment of Autoimmune Diseases with Heat Shock Proteins

Published in Vaccine Weekly, January 19th, 2000

Antigenics, L.L.C. announced the issuance of a patent with broad claims covering methods of treatment of autoimmune diseases, such as type 1 diabetes and multiple sclerosis, with heat shock proteins.

The patent is the ninth issued in the United States for which Antigenics has exclusive worldwide rights.

The company's lead product candidate for treatment of autoimmune diseases is the heat shock protein gp96, which has demonstrated efficacy in animal models of type 1 diabetes and multiple sclerosis. Antigenics has also made progress in elucidating the mechanism by which heat shock proteins modulate the immune system to treat these diseases.

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